![]() What it's like to stay on Ozempic for years.Wegovy shown to cut risk of stroke and heart attacks, company says.Michael Natter, an endocrinologist at NYU Langone Health, cautioned. We need to see more and larger studies,” Dr. “You can’t make too much of a claim based on a small, non-controlled study. What comes nextĮxperts welcomed the new study, but said there needed to be more research before any changes in treatment were recommended. “While we have not had the opportunity to evaluate this data, we support research for potential advancements of treatments for patients with Type 1 diabetes as well as other serious chronic conditions,” Schneider said. “The study in the NEJM was not sponsored by Novo Nordisk and we currently do not have any studies ongoing with semaglutide in people living with Type 1 diabetes,” company spokesperson Allison Schneider said in an email. Novo Nordisk, the maker of semaglutide, isn't doing research on Type 1 diabetes and semaglutide. Once funding has been secured, the study can start. That medication, which also mimics GLP-1, reduced the amount of insulin patients needed but not as dramatically as what he described in the new report.īefore that happens, there needs to be a much larger and longer study, Dandona said, adding that he’s already rounded up a group of diabetes investigators from various centers around the country. In 2011, Dandona had tried treating patients with Type 1 diabetes with a related but less effective medication, liraglutide. Semaglutide helps with Type 2 diabetes by mimicking a hormone in the body called GLP-1, which is released in the digestive system after eating and prompts the body to make more insulin, which in turn lowers blood sugar. Drugs for Type 2 diabetes work in different ways, including lowering blood sugar, increasing insulin sensitivity and increasing insulin production. In addition, the body doesn’t respond well to the insulin that is produced, a condition known as insulin resistance. In Type 2 diabetes, the beta cells in the pancreas are not attacked, but they do not produce enough insulin. People with Type 1 diabetes must therefore take insulin, because their bodies cannot make it. Insulin is a molecule that tells the body to move sugar from the blood into cells, where it can be used for energy. In Type 1 diabetes, the body mistakenly attacks and destroys beta cells in the pancreas that produce insulin. Type 1 diabetes is an autoimmune disease. But the causes of the conditions - and how they are treated - are different. People with Type 1 and Type 2 diabetes both have trouble controlling blood sugar levels. “It was almost like science fiction,” said Dandona, a professor of medicine at the University at Buffalo’s Jacobs School of Medicine and Biomedical Sciences in New York.
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